منابع مشابه
The Human Genome Epidemiology Network.
Progress on the Human Genome Project has led to an explosion of genetic information (1). Of the estimated 100,000 human genes, more than 9,000 have been discovered, and more than 5,000 have been mapped to specific chromosomes (2). There are approximately 500 genes for which there are genetic tests used in medical practice (3). Almost daily, discoveries are announced for gene variants that affec...
متن کاملHuman genome epidemiology, progress and future
Human genome epidemiology (HuGE) uses systematic applications of epidemiologic methods to assess the impact of human genetic variation on health and disease. In the past ten years, human genome epidemiology has made great progresses along with advances in genomics technologies, which make it possible for the examination of genetic variants in a large sample size at a sufficiently low cost. Gene...
متن کاملOnline genetic databases informing human genome epidemiology
BACKGROUND With the advent of high throughput genotyping technology and the information available via projects such as the human genome sequencing and the HapMap project, more and more data relevant to the study of genetics and disease risk will be produced. Systematic reviews and meta-analyses of human genome epidemiology studies rely on the ability to identify relevant studies and to obtain s...
متن کاملMolecular Epidemiology of Human Papillomavirus in Pterygium
Abstract Background and Objective: Ophthalmic pterygium is a potentially vision-threatening lesion of unknown etiology that often extends on the corneal surface and has a worldwide distribution. Despite various studies, the pathogenesis of pterygium remains unclear and the involvement of human papillomavirus is controversial. We aimed to investigate the involvement of papillomavirus in pte...
متن کاملA network of investigator networks in human genome epidemiology.
The task of identifying genetic determinants for complex, multigenetic diseases is hampered by small studies, publication and reporting biases, and lack of common standards worldwide. The authors propose the creation of a network of networks that include groups of investigators collecting data for human genome epidemiology research. Twenty-three networks of investigators addressing specific dis...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2004
ISSN: 0002-9297
DOI: 10.1086/423739